The U.S. and Israel Launch Major Military Strikes on Iran, Khamenei Reported Dead

The U.S. and Israel Launch Major Military Strikes on Iran, Khamenei Reported Dead
KHAMENEI.IR via AFP via Getty Images

The United States and Israel launched what the Pentagon dubbed “Operation Epic Fury” in the early hours of Saturday morning, striking targets across Iran with the stated aim of destroying the country's military capabilities, dismantling its nuclear program, and fostering regime change. President Trump announced the operation in a 2:30 A.M. video posted to Truth Social, declaring that Iran has engaged in decades of “mass terror” and promising the U.S. would “annihilate their navy” and “raze their missile industry to the ground.”

The strikes targeted Tehran and sites across the country. Satellite imagery and verified video showed smoke rising over the capital, including near the compound of Supreme Leader Ali Khamenei and the presidential palace. Israel's Air Force struck Iranian senior commanders and political leaders in a parallel operation it named “Lion's Roar,” while closing Israeli airspace, declaring a state of emergency, and calling up roughly 70,000 reservists.

Iran retaliated swiftly, launching missiles at U.S. bases in Qatar, Saudi Arabia, Bahrain, Kuwait, Iraq, the UAE, and Jordan. A senior U.S. official reported no American casualties as of mid-Saturday morning. The UAE said it intercepted several missiles but that one person in Abu Dhabi died from falling debris. In Iraq, U.S. strikes hit sites near Baghdad linked to the Iran-backed militia Kata'ib Hezbollah, whose leaders vowed to strike back. Jordan intercepted two missiles in its airspace.

Saturday afternoon, the U.S. and Israel reported that Iranian Supreme Leader Ali Khamenei was killed in an Israeli strike, along with seven senior defense and intelligence officials. Khamenei led Iran for over 35 years.

The operation came after a final round of U.S.-Iran nuclear talks ended Thursday without a breakthrough, exactly as Trump's 10-day ultimatum expired. Trump called on Iranian citizens to overthrow their government once the strikes concluded, saying it would be “probably your only chance for generations.” He also acknowledged the likelihood of American casualties, saying the “lives of courageous American heroes may be lost.”

This comes after the U.S. struck Iran last June, when they targeted nuclear enrichment sites Fordow, Natanz, and Isfahan. At that time and since, the Trump administration said Iran’s nuclear program had been “totally obliterated.” But during the State of the Union address on Tuesday, President Trump said that Iran had restarted its nuclear program. “They were warned to make no future attempts to rebuild their weapons program, and in particular nuclear weapons, yet they continue,” he said, adding, “They're starting it all over. We wiped it out, and they want to start it all over again and are at this moment again pursuing their sinister ambitions.”

In the weeks leading up to this, the U.S. has been building a massive arsenal in the region.

Note: Some U.S. ship locations are approximate. Source: New York Times reporting and analysis of satellite imagery, ship- and flight-tracking data. The New York Times
Note: Some U.S. ship locations are approximate. Source: New York Times reporting and analysis of satellite imagery, ship- and flight-tracking data. The New York Times

More News

🎤 Trump Delivers Longest-Ever State of the Union: The President broke his own record Tuesday night with a speech that lasted 1 hour and 48 minutes. He stuck to the script, outlining a litany of his administration’s accomplishments, and delivered numerous made-for-TV moments: welcoming the Olympic gold-medal hockey team to a bi-partisan standing ovation— before awarding Purple Hearts, a Medal of Honor to the lead helicopter pilot who sustained injuries in the operation that captured Venezuelan president Nicolas Maduro, and a Medal of Freedom to Team USA goalie Connor Hellebuyck. The President also awarded the Legion of Merit to Scott Ruskin, the Coast Guard swimmer who saved 165 people in Texas floods. A CNN snap poll found 64% of viewers reacted positively, and the same percentage said after the speech that they felt the administration had “the right priorities.” Virginia Governor Abigail Spanberger delivered the Democratic response, centering her rebuttal on affordability and asking viewers whether the President was working to make their lives more affordable.

Data: The American Presidency Project. Chart: Axios Visuals
Data: The American Presidency Project. Chart: Axios Visuals

🇲🇽 Mexican Cartel Boss “El Mencho” Killed: Mexico's military killed Nemesio Oseguera Cervantes, known as “El Mencho,” the leader of the Jalisco New Generation Cartel, last Sunday in a targeted raid that also eliminated four cartel fighters. The White House confirmed the U.S. provided intelligence support for the operation. His death triggered terror attacks across Mexico — gunmen set fire to buildings and vehicles, deployed roadblocks, and carjacked civilians in at least a dozen states, killing at least 62 people and sending cities, including Puerto Vallarta, into chaos. By the middle of the week, the violence had quieted down.

Sources: Verified footage; Ministry of Security and Citizen Protection. Pablo Robles and Devon Lum/The New York Times
Sources: Verified footage; Ministry of Security and Citizen Protection. Pablo Robles and Devon Lum/The New York Times

🔒 Mar-a-Lago Breach Ends in Fatal Shooting: Secret Service agents and a Palm Beach County deputy shot and killed21-year-old Austin Tucker Martin of North Carolina after he drove into Mar-a-Lago's secure perimeter Sunday carrying a shotgun and a gas can. Martin raised the weapon toward officers after being ordered to drop it. President Trump was in Washington at the time, and the FBI asked local residents to check security cameras for footage that could aid the investigation.

🗳️ Texas Senate Primary Becomes Most Expensive Ever: Tuesday's primary has drawn more than $110 million in spending, with roughly $75 million coming from outside groups. On the Republican side, incumbent Senator John Cornyn and Attorney General Ken Paxton are expected to head for a May runoff, while Democrats Jasmine Crockett and James Talarico are locked in a fierce race with early voting exceeding presidential-level turnout.

🤖 Block Cuts 40% of Workforce, Replaces Jobs with AI: Jack Dorsey announced Wednesday that Block—parent of Square, Cash App, and Afterpay—would eliminate more than 4,000 of its 10,000 employees, citing AI tools that enable smaller teams to do more. The move sent the stock up as much as 25% in premarket trading.

🌨️ Record Blizzard Buries New England: A massive storm dumped nearly 20 inches of snow on Central Park and a record-shattering 33 inches on Providence, Rhode Island, stranding hundreds of cars on Massachusetts highways and bringing much of the region to a standstill.

Photo: Ryan Murphy/Getty Images
Photo: Ryan Murphy/Getty Images

🏠 Mortgage Rates Dip Below 6% for First Time Since 2022: The 30-year rate crossed below a key psychological threshold this week, expected to boost spring home sales. Experts caution that refinancing only makes sense if you can lock in a rate at least half a point below your current one and plan to stay in your home for at least four years to offset surging closing costs.

✈️ Global Entry Suspended: After the Department of Homeland Security’s funding lapsed due to a congressional squabble over ICE and deportations, the department announced it was suspending the Global Entry trusted-traveler program in an effort to save costs.